UV Disinfection Solution for Pharmaceutical Industry

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Delivering purified and high quality water for pharmaceutical industry

Water is one of the most important and essential requirements in the pharmaceutical sector. Water used for manufacturing of pharmaceutical products must be free of pathogens, and chemicals such as chlorine and ozone. Pharmaceutical businesses must treat their input water sources to get rid of any contaminants or pathogens that could lower the quality of their products.

UV disinfection is a rapid, reliable and inexpensive way to disinfect water for use in pharmaceutical manufacturing processes which require pathogen-free water. Pharmaceutical UV disinfection systems from Alfaa UV, provides water of the right quality, required to meet the stringent standards of regulatory bodies like the FDA and Good Manufacturing Practice (GMP).

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Application notes for Pharmaceutical Industry

  • UV Disinfection for Potable Water
  • UV Disinfection for WasteWater Treatment
  • UV Disinfection in Cold Water for Injection Distribution Loop
  • UV Disinfection for Pre-Treatment Systems
  • UV Disinfection for Purified Water Distribution Loop

Case Studies for Pharmaceutical Industry

  • UV Disinfection for Cold Loop - A Case Study
  • UV Disinfection for Toc Reduction - A Case Study
  • UV Disinfection for Delivery And Return Line In Distribution Loop - A Case Study
  • UV Disinfection for Ozone Destruction - A Case Study
  • UV Disinfection for Raw Water/Potable Water Post Filtration - A Case Study

Significance of water treatment in the pharmaceutical industry

Alfaa UV products ensure purified & disinfected water for pharma use

In the pharmaceutical sector, purified water is used in multiple ways.

  • Component for manufacturing of medical products: For some medicines, water can be a critical component. Ordinary water, including drinking water, contains traces of pollutants and toxins, and hence cannot be used as a medicinal ingredient. Purified and disinfected water is required for this application.
  • Boiler & cooling water: Treated water is required in the boiler and cooling water systems of pharma manufacturing plants. Lack of adequate water treatment might cause bacteria and sediments in the boiler housing and pipes to interact. Scale deposits can also mean that more fuel is needed to heat the same amount of water due to a loss in efficiency. In addition, untreated water can support the growth of bacteria like Legionella, endangering public health.

UV disinfection to address Pseudomonas aeruginosa contamination in pharma companies

Alfaa UV products ensure safe water for pharmaceutical industry.

Water contamination from Pseudomonas aeruginosa is a serious concern in pharmaceutical manufacturing. This occurs primarily in main water source, water treatment plants, water-based systems such as cooling towers, water storage and distribution tanks. Cross-contamination by Pseudomonas aeruginosa may also occur in water injection tanks, pipelines, and water used for industrial processes.

When water utilized for pharmaceutical manufacturing is contaminated with Pseudomonas, it can result in alterations in the chemical characteristics of the medicines. The bacteria can put human health at risk especially immuno-compromised patients. In instances where Pseudomonas contamination has been confirmed by microbiological tests, it can lead to a series of consequential events including product recalls, regulatory action, and hindrance to the manufacturer’s reputation.

UV disinfection is an effective and non-chemical method for addressing Pseudomonas contamination for pharma companies. It successfully eliminates the problem of accumulation of chemical residues that could contaminate pharmaceutical products. UV water treatment is often used in combination with ozonation to enhance the treatment efficiency. The water undergoes treatment with ozone first, and then it is subjected to UVC light.

For further details, please refer to our blog on use of UV disinfection to address P. Aeruginosa contamination in pharma companies.

Leading UV disinfection for pharma industry

Alfaa UV is the market leader for UV disinfection systems in India. Our esteemed customers include GSK, Astra Zeneca, Eli Lilly, Johnson & Johnson, Pfizer, Merck Sharpe & Dohme, Novartis, Rhone Poulenc, Torrent Pharma, Sun Pharma, Cipla, Dr. Reddys Laboratories, Sanofi, Pharmazeil, Panacea Biotec, Baxter, Centaur, Indoco Remedies, Hetero Labs, Ipca, Alembic and Reckitt Benckiser.

Alfaa UV’s market leadership is supported by our:

  • Two decades of experience in the UV disinfection space
  • Strong R&D capabilities
  • World-class manufacturing facility in Talegaon, Maharashtra
  • State-of-the-art UV disinfection systems, which have been installed in India as well as in over 15 other countries
  • Eco-friendly technology – our products use no chemicals in the cleaning process
  • Compliance assurance – our UV disinfection systems meet stringent regulations
  • Quality management standards, certified by ISO 9001

In fact, Alfaa UV has dominated the UV disinfection space in India for the past two decades, having installed more than 2,000 systems for pharma companies.

Why choose Alfaa UV for water disinfection in pharma industry?

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A typical installation at a Pharma site

Water disinfection systems from Alfaa UV are used in the pharmaceutical industry for the following applications:

To learn more about the effectiveness of UV water disinfection for the pharmaceutical industry, please refer to our blog.

UV disinfection is a rapid, effective, and inexpensive way to disinfect water for use in pharmaceutical manufacturing processes which require pathogen-free water. During the disinfection process, UV sterilizers are used to expose the water to UV rays of specific wavelengths, which kill pathogens present in the water such as bacteria, viruses, algae, molds, etc., and prevent them from replicating.

One of the main applications of UV disinfection, aside from manufacturing of medical products, is Cleaning in Place (CIP), a method used in the pharmaceutical industry to clean the vessels, apparatus, pipelines, filters, and other accessories used in routine manufacturing activities. Not only does UV help pharmaceutical businesses to adhere to Good Manufacturing Practice requirements (GMP), but also ensures the safety of liquid orals and extends the shelf life of such products.

UV disinfection systems are also used for pharmaceutical wastewater treatment for reuse or discharge.

Some of the key benefits of UV technology for water disinfection are:

  • Excellent performance: Disinfection with UV systems decreases the risk of waterborne diseases without altering the pH and chemistry of the water.
  • Environmental safety: The uncontrolled release of chlorinated compounds into the environment has created a global environmental problem. Alfaa UV uses environmentally friendly UV technology for water disinfection. In fact, no chemicals are used during the disinfection process.
  • Lower operating costs: Sodium hypochlorite or ‘liquid chlorine’ is expensive, with high running and associated handling costs. On the other hand, UV water disinfection systems are cost-effective. A typical payback period for UV systems is less than 2 years.
  • No harmful by-products: Trihalomethanes and other toxic chlorine by-products are known to cause cancer in humans. UV water disinfection is a natural, chemical-free process that produces no trihalomethanes or carcinogens.
  • Easy handling: Chlorine disinfection creates operational and logistical hassles, such as repeated procurement, storage, handling, dilution and mixing. It requires constant attention and supervision. UV disinfection system utilises no chemicals, works online, and requires minimal supervision and maintenance.
  • Operator safety: Leaks and spills of chlorine may lead to burns, permanent vision damage and lung damage. UV disinfection systems do not have any risks with handling, safety, flammability or explosion.

In addition, Alfaa UV offers the following specific advantages.

  • Best-in class expertise: Alfaa UV has been at the forefront of installing environmentally-friendly UV purification technology for the disinfection of air and water at some of India’s prominent companies, over the past two decades.
  • Quality assurance: Our design and manufacturing capabilities, based on cutting-edge technologies, have ensured excellent quality output for our clients.
  • Right-sizing: UV disinfection solutions from Alfaa UV are customised for your specific requirements. We ensure that your UV systems are designed to function effectively, as incorrect sizing can decrease your UV system's efficacy and impact performance.
  • Regulatory compliance: Alfaa UV will enable you to meet the stringent regulatory requirements for water treatment. We provide comprehensive documentation support for your audit processes. UV disinfection systems from Alfaa UV are (UL & CE certified). This system is designed as per NSF standard.
  • Excellent service: Alfaa UV offers robust customer support and service to ensure that your UV disinfection systems are operating effectively and consistently, with minimum downtime. Whether you need phone support, on-site maintenance, or just want to acquire a replacement part, we are always there for you.

To know more about our products and how we can support your business, do get in touch with us.

Alfaa UV’s excellence in UV disinfection for the pharmaceutical industry

Alfaa UV has a wide range of products for water disinfection for pharmaceutical companies:

  • BioPure UV Systems are especially designed as per ASME BPE norms which are the most stringent norms in the biotech/ pharma industry.
  • Alfaa HiFlo Series of UV purification systems delivers the highest water quality and reliable performance for the pharmaceutical industry.
  • APi UV Lamp Series from Alfaa UV has earned the trust and goodwill of some of the most reputed pharma companies in India.
  • Alfaa UV’s WWR Series addresses the growing need for a reliable & environmentally responsible way to disinfect and reuse wastewater for the pharma industry.

How Alfaa UV addressed treated water requirement for a leading company in the health & wellness sector

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Case Study

Alfaa UV’s customer is a leading Indian health and wellness company with interests in hair care, oral care, health care, skin care, home care and food & beverages.


Water is a key ingredient in the manufacturing of various products by Alfaa UV’s customer. As per the cGMP norms such as & HACCP, HAZOP, FSSAI there is a need for clean, microbial free and safe water. Chlorine & other chemically treated water cannot be used as it may impact the raw material, process application, and the finished products.

The company was facing challenges in using water of the right quality for the following applications:

  • Washing bottles & process vessels
  • Washing of product & raw materials
  • Use of water in products
  • Manufacturing process application
  • Recycling of waste water

Solution from Alfaa UV:

Based on the flow rate and quality of water available at the manufacturing plant, Alfaa UV installed the HF and APi series of products for purifying the water being utilised in the manufacturing processes. Superior features of the HF and APi series include internal electropolishing which make these UV sterilizers resistant to stain and bacteria. Installing Alfaa’s UV disinfection products in the water treatment plant created the ideal water for manufacturing a large range of products, to improve the hygiene and safety, and to prolong product shelf life. Our customer is now able to meet the required water quality standards in accordance with FDA's stringent criteria.

Real-time remote performance monitoring of water disinfection systems

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Real-Time Monitoring

Alfaa UV is in the process of launching IoT-based remote monitoring of UV disinfection systems. IoT-based remote performance monitoring will deliver multiple benefits to Alfaa UV’s customers, including:

  • Real-time monitoring and control: Continuous monitoring of important parameters such as UV intensity and dosage, which determine the purity levels of the treated water.
  • Alerts: Immediate alerts in case of system malfunctions or when the above parameters deviate from the set norms.
  • Predictive maintenance: Predict when the system requires maintenance, thereby preventing unexpected downtimes.
  • Safety: In case of a critical failure, the system can be shut down remotely to prevent any safety incidents or damage to the system, thereby saving costs in repair and maintenance.
  • Remote troubleshooting: Alfaa UV engineers can diagnose and troubleshoot issues remotely, reducing downtime and operational costs.
  • Record-keeping: Remote logging maintains a secure and easily accessible database of operational data to demonstrate compliance with regulatory standards.
  • Transparency: Sharing performance dashboards with the management and the regulatory authorities will build trust and support by demonstrating effectiveness and safety of the treatment process.

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